Twelve Things You Should Know About Tramadol

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Tramadol is the generic version of Ultram and is a synthetic analgesic medication. Tramadol binds to opioid receptors in the brain that transmit the sensation of pain throughout the body.

Here are ten things you should know about Tramadol to ensure its appropriate and safe use:


  1. Tramadol is prescribed to treat moderate to moderately severe pain.
  2. Tramadol belongs to the class of drugs known as opiate agonists. Tramadol works by changing the way the body senses pain. It is prescribed for people who suffer from mild to severe pain in the body.
  3. Tramadol is available in immediate release and extended release formulations. Tramadol may be prescribed as an immediate release tablet(50mg) or as an extended release tablet(100,200 or 300mg). The extended release tablets are usually reserved  for patients with chronic pain who require continuous long-term treatment. The doctor will determine the appropriate dosage for you.
  4. Tramadol extended release tablet must be taken as a whole, not chewed or crushed. It is important to take Tramadol properly and to follow prescribed instructions. If not taken properly, or if not recommended, then serious side effects occur and it could be fatal for the patient.
  5. Tramadol can be habit-forming.
  6. Do not take more than it has been prescribed for you.
  7. Taking more Tramadol  or taking it more often can cause dependency on it. You should also not stop taking Tramadol without first consulting your doctor. You may experience withdrawal symptoms if you stop it suddenly. The doctor will likely decrease your dose of Tramadol gradually.
  8. Drug interactions are possible with Tramadol. Be aware of the following possible drugs:

Carbamazepine reduces the effect of Tramadol.

Quinidine increases the concentration of Tramadol by 50% to 60%

Combining tramadol with an MAO (monoamine oxidase inhibitor) inhibitor or SSRI         (selective serotonin reuptake inhibitors) can lead to seizures or other serious side     effects.

  1. Tramadol, when combined with other substances, can increase central nervous system, and respiratory depression
  2. Be sure to tell your doctor about all of the medications and supplements you take. In other words, breathing may be affected or even stopped if Tramadol  is combined with alcohol, narcotic drugs, anesthetic, or sedatives.
  3. The use of Tramadol during pregnancy should be avoided. Because the safety of Tramadol use during pregnancy has not been established, therefore the medication should not be used during pregnancy as it may be harmful to the new born babies.
  4. Tramadol is usually well tolerated, any side effects are usually temporary. Some common side effects associated with Tramadol include:
  • Nausea
  • Constipation
  • Dizziness
  • Vomiting
  • Headache
  • Drowsiness
  • Less common side effects are
  • Sweating
  • Itching
  • Diarrhea
  • Dry mouth
  • Rash
  • Seizures
Twelve Things You Should Know About Tramadol

Twelve Things You Should Know About Tramadol

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